I’m in the planning stages of a build that will be essentially this, a proxmox build that’ll include my NAS with several hard drives (running in one VM), all my docker containers (another VM) and Linux and Windows vms with passthrough that I can spin up temporarily for games.
I think I can get the Windows VM in a place where I can also restart the whole machine and boot in natively, as a fallback for games with aggressive anti cheats that won’t allow VMs, which I don’t think I’ll be playing much of anyway.
To answer your question, it really would be best to check game by game if the anti cheat allows VMs.
I think my favorite part is how they’ve brought back software rendering, both by allowing it on linux and by giving the option to turn off texture filtering on opengl. That plus making the main menu look like the original release brings me right back to how I first played Half-Life!